Sleep Deprivation, Alcohol Use Have Greater Deleterious Effects on Driving Ability in Patients with Sleep Apnea

Patients with obstructive sleep apnea (OSA) are more likely to experience simulated car crashes after partial sleep deprivation or low alcohol consumption compared with people without apnea, according to a driving simulator study in Annals of Internal Medicine.
Nearly 40 patients with OSA and 20 controls underwent a 90-minute driving task under three conditions: unrestricted sleep, partial sleep restriction (maximum 4 hours' sleep on 1 night), and low-dose alcohol consumption (blood alcohol target, 0.05 g/dL).
Patients with OSA had greater steering deviation under all three conditions than did controls. OSA patients were also more likely to have crashes — 10% after unrestricted sleep, 21% after alcohol consumption, and 32% after sleep deprivation (only one control had a crash).
The authors conclude that "it may be advisable" for patients with OSA "to avoid even legal doses of alcohol or sleep restriction before driving or performing other tasks in which safety is a factor."

(Annals of Internal Medicine. 06 October 2009. Volume 151, Issue 7: Pages 447-455.)

Link to abstract